Methods of storing information using nucleic acids
AssigneePresident and Fellows of Harvard College
InventorGeorge M. Church
Life of this patent
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Abstract
The present invention relates to methods of storing data using one or more nucleic acids including converting a format of information into a plurality of bit sequences of a bit stream with each having a corresponding bit barcode, converting the plurality of bit sequences to a plurality of corresponding oligonucleotide sequences using one bit per base encoding, synthesizing the plurality of corresponding oligonucleotide sequences, and storing the synthesized plurality of corresponding oligonucleotide sequences.
Claims16
A method of storing information using nucleotides comprising
- converting a format of information into a plurality of bit sequences of a bit stream with each having a corresponding bit barcode,
- converting the plurality of bit sequences to a plurality of corresponding oligonucleotide sequences using one bit per base encoding,
- synthesizing the plurality of corresponding oligonucleotide sequences, and
- storing the synthesized plurality of corresponding oligonucleotide sequences.
A method of retrieving a format of information from a plurality of synthesized oligonucleotide sequences encoding bit sequences of the format of information comprising
- amplifying the plurality of oligonucleotide sequences,
- sequencing the amplified oligonucleotide sequences,
- converting the oligonucleotide sequences to bit sequences, and
- converting the bit sequences to the format of information.
A method of accessing a format of information from a plurality of synthesized oligonucleotide sequences encoding bit sequences of the format of information comprising
- amplifying the plurality of oligonucleotide sequences,
- sequencing the amplified oligonucleotide sequences,
- converting the oligonucleotide sequences to bit sequences,
- converting the bit sequences to the format of information, and
- visualizing the format of information.
A method of storing information using nucleotides comprising converting a format of information to a bit stream, encoding first bit sequences into corresponding oligonucleotide sequences, synthesizing the oligonucleotide sequences, sequencing the oligonucleotide sequences, decoding the oligonucleotide sequences into bit sequences, assembling the bit sequences into a bit stream and converting the bit stream into the format of information.
A method of storing information using nucleotides comprising converting a format of information to a first bit stream, encoding first bit sequences into corresponding oligonucleotide sequences, synthesizing the oligonucleotide sequences, sequencing the oligonucleotide sequences, decoding the oligonucleotide sequences into second bit sequences, assembling the second bit sequences into a second bit stream and converting the second bit stream into the format of information.
A method of storing information using nucleotides comprising converting a first format of information to a first bit stream, encoding first bit sequences into corresponding oligonucleotide sequences, synthesizing the oligonucleotide sequences, sequencing the oligonucleotide sequences, decoding the oligonucleotide sequences into second bit sequences, assembling the second bit sequences into a second bit stream and converting the second bit stream into a second format of information.
A method of retrieving a format of information from a plurality of synthesized oligonucleotide sequences encoding bit sequences of the format of information comprising
- sequencing the amplified oligonucleotide sequences,
- converting the oligonucleotide sequences to bit sequences, and
- converting the bit sequences to the format of information.
A method of accessing a format of information from a plurality of synthesized oligonucleotide sequences encoding bit sequences of the format of information comprising
- sequencing the amplified oligonucleotide sequences,
- converting the oligonucleotide sequences to bit sequences,
- converting the bit sequences to the format of information, and
- visualizing the format of information.
Dependencies are inferred from the claim text.