Methods of making a deuterated or a non-deuterated molecule and pharmaceutical formulations for treatment
OwnerBhupinder Singhinventor
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Abstract
Deuterated and non-deuterated forms of tetrahydrocurcumin are described herein. Methods of making tetrahydrocurcumin in deuterated and non-deuterated forms and pharmaceutical formulations including tetrahydrocurcumin in deuterated and non-deuterated forms are disclosed. Methods of treating a subject using deuterated forms of tetrahydrocurcumin or non-deuterated forms of tetrahydrocurcumin are also disclosed.
Claims32
A method of treating, inhibiting, or ameliorating a disorder in a subject, the method comprising:
- identifying a subject having a disorder selected from the group consisting of alcoholic liver disease, hypertension with left ventricular hypertrophy, and cardiac hypertrophy;
- and
- administering a pharmaceutical formulation to the subject, the pharmaceutical formulation comprising a non-deuterated form of tetrahydrocurcumin or a deuterated form of tetrahydrocurcumin and a pharmaceutical vehicle.
A method of protecting an organ, comprising:
- identifying a subject in need of protection of an organ, the organ selected from kidney, liver and heart;
- and
- administering a pharmaceutical formulation to a subject in need thereof, the pharmaceutical formulation comprising a deuterated form of tetrahydrocurcumin at greater than natural isotopic abundance and a pharmaceutical vehicle.
A method of treating or preventing heart failure in a subject in need, comprising:
- identifying a subject in need of treatment for or prevention of heart failure;
- and
- administering pharmaceutical formulation to a subject in need thereof, the pharmaceutical formulation comprising a deuterated form of tetrahydrocurcumin at greater than natural isotopic abundance and a pharmaceutical vehicle.
A pharmaceutical formulation comprising a deuterated form of tetrahydrocurcumin at greater than natural isotopic abundance and a pharmaceutical vehicle.
Dependencies are inferred from the claim text.