Newcastle disease virus and the use thereof as a vaccine
AssigneeInvestigación Aplicada S.A. de C.V.
InventorsJosé Andrés Garzón Morales, Eduardo Lucio Decanini, Diana Verónica Cortes-Espinosa, Angel Eduardo Absalon-Constantino
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Abstract
The present invention relates to a new Newcastle disease viruses of any genotype and novel fragments of the Newcastle disease virus genome encoding for the F and HN proteins constructed by reverse genetics and recombination, highly antigenic, for preparing vaccines for the prevention of the Newcastle disease by reducing viral shedding or for using as vectors with other viruses, lyophilized or in oil emulsion. Likewise, it can be used as vector in combination with other pathogenic agents.
Claims19
A recombinant Newcastle disease virus containing nucleotide sequences encoding NP, P, M, L, F and HN proteins, wherein the nucleotide sequence encoding the F and HN proteins comprises the nucleotide sequence of SEQ ID NO:
- 1.
A vector comprising the nucleotide sequence of SEQ ID No 1.
An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.