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US 9,358,093 B2Granted
Bio-implantable devices having super-hydrophobic surface and method for manufacturing thereof
AssigneeKorea Institute of Science and Technology
InventorsSoo Hyun Kim, Jin Ik Lim, Youngmee Jung
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Abstract
The present disclosure relates to a bioimplantable device having a superhydrophobic surface and a method for manufacturing the same. The bioimplantable device, which includes a biocompatible substrate and a superhydrophobic nanostructure formed on the surface of the biocompatible substrate, is capable of preventing blood clot formation by blocking contact with proteins, water, blood platelets, etc. when used for blood vessels.
Claims8
A method for manufacturing an anti-thrombogenic bioimplantable device having a superhydrophobic surface, comprising:
- forming a nanoporous metal oxide film on the surface of a biocompatible substrate;
- forming a nanostructure on the biocompatible substrate by subjecting the biocompatible substrate having the nanoporous metal oxide film formed to a temperature of 60-250° C. and the pressure of 0.01-0.5 Mpa;
- removing the nanoporous metal oxide film remaining on the portion where the nanostructure is not formed by treating the biocompatible substrate having the nanostructure formed with a metal oxide film removing solution;
- and
- washing the biocompatible substrate having the nanoporous metal oxide film removed with alcohol and distilled water and then drying,
- wherein before said forming the nanoporous metal oxide film, applying one or more solvent selected from a group consisting of chloroform, acetone, tetrahydrofuran, toluene, xylene and dioxane on the surface of the biocompatible substrate.
3 more elements
Dependencies are inferred from the claim text.