LPS vaccine
AssigneeThe Chemo-Sero-Therapeutic Research Institute
InventorsRyuichi Sakamoto, Masashi Sakaguchi
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Abstract
A vaccine composition for birds comprising as an active ingredient a structure containing O-antigen derived from Gram-negative bacteria, provided that said structure does not contain a whole cell, and a process for preparing the same are provided. By using a structure containing O-antigen (e.g. lipopolysaccharide) derived from Gram-negative bacteria as an active ingredient in accordance with the present invention, alleviation of inoculation reaction and reduction in an amount of injection are attained as compared to the conventional whole-cells vaccine to thereby allow for the increase in the number of other antigens to be mixed therewith.
Claims12
A salmonella vaccine composition for birds comprising purified lipopolysaccharide O-antigens from Salmonella Enteritidis, Salmonella Typhimurium, and Salmonella Infantis, provided that said O-antigens are not comprised in a whole cell;
- and at least one additional antigen selected from the group consisting of an antigen from Newcastle disease virus, an antigen from avian infectious bronchitis virus, an antigen from Mycoplasma gallisepticum, an antigen from Egg drop syndrome virus and an antigen from Haemophilus paragallinarum.
Dependencies are inferred from the claim text.