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US 9,340,536 B2Granted
Multicomponent crystals comprising dasatinib and selected co-crystal formers
AssigneeBASF SE
InventorsTiziana Chiodo, Andreas Hafner, Tobias Hintermann, Beate Salvador, Martin Szelagiewicz, Fritz Blatter, Bernd Siebenhaar, Marcus Vossen
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Abstract
Provided are a multicomponent crystalline system (co-crystal), use thereof, as well as a process for obtaining the same. The said multicomponent crystalline system (co-crystal) comprises Dasatinib and a second compound selected from methyM-hydrobenzoate, nicotinamide, ethyl gallate, methyl gallate, propyl gallate, ethyl maltol, vanillin, menthol, or (1R,2S,5R)-(−)-menthol.
Claims19
A multicomponent crystalline system, comprising:
- a compound of formula 1
- and
- a second compound selected from the group consisting of methyl-4-hydroxybenzoate, nicotinamide, ethyl gallate, methyl gallate, propyl gallate, ethyl maltol, vanillin, menthol, and (1R,2S,5R)-(−)-menthol.
Dependencies are inferred from the claim text.