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US 9,333,478 B2Granted
Support carrying an immobilized selective binding substance
AssigneeToray Industries, Inc.
InventorsKunihisa Nagino, Fumio Nakamura, Hitoshi Nobumasa
Life of this patent
Estimating the term…
Abstract
A support carrying an immobilized selective binding substance, that the support surface has a polymer containing the structural unit represented by the following General Formula (1) in an amount of 10% or more with respect all monomer units, and a selective binding substance is immobilized on the support surface by binding to the carboxyl group formed thereon via a covalent bond: (in General Formula (1), R1, R2, and R3 each represent an alkyl or aryl group or a hydrogen atom.)
Claims11
A support carrying an immobilized selective binding substance comprising:
- a concavo-convex part containing multiple projections and a flat area surrounding the concavo-convex part, wherein the selective binding substance is immobilized on a surface of top faces of the multiple projections, a difference in height between the top faces of highest and lowest projections of the multiple projections is 50 μM or less, the top faces of the multiple projections are substantially flat, and wherein the flat area is free of concavo-convex structures and higher in height than the top faces of the multiple projections, in which the difference in height between the top faces of the highest projections of the multiple projections and the top face of the flat area is 100 μM or less, the support has a surface with a polymer comprising a structural unit represented by Formula (1), the support surface of the polymer being treated with an alkali or acid, forming carboxyl groups and the selective binding substance is essentially immobilized only on the surface of the top faces of the multiple projections of the concavo-convex portion through the carboxyl groups
- wherein R1, R2 and R3 each represent an alkyl or aryl group or a hydrogen atom.
Dependencies are inferred from the claim text.