# US 9,320,602 B2 · Compressed fiber structural material and method for producing the same > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,320,602 B2 - Document ID: US9320602B2 - Status: Granted - Kind: B2 - Application number: 14/345,668 - Filed: 2012-03-09 - Published: 2014-11-13 - Granted: 2016-04-26 - Earliest claimed: 2011-09-20 - Assignees: Shinshu University - Applicants: Noboru Nakayama; Masaomi Horita; Naoki Izawa; Hiroto Tamai; Naoto Saito; Yuki Usui; Nobuhide Ogihara - Inventors: Noboru Nakayama; Masaomi Horita; Naoki Izawa; Hiroto Tamai; Naoto Saito; Yuki Usui; Nobuhide Ogihara - Web page: https://patentgrep.com/patent/US9320602B2 ## CPC - A61F 2/28: Bones - A61L 27/04: Metals or alloys - B22F 3/002: {Manufacture of articles essentially made from metallic fibres} - C22C 49/11: Titanium - C22F 1/183: {of titanium or alloys based thereon} - A61F 2002/2835: {Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material} - A61F 2310/00023: Titanium or titanium-based alloys, e.g. Ti-Ni alloys - A61F 2310/00425: Coating made of magnesium or of Mg-based alloys - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - B22F: WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER (making alloys by powder metallurgy C22C); APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER - C22C: ALLOYS (treatment of alloys C21D, C22F) - C22F: CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS (surface treatment of metallic material involving at least one process provided for in class C23 and at least one process covered by this subclass, C23F17/00) ## Abstract Provided is a method for easily producing a lamellar compressed fiber structural material which has mechanical characteristics close to those of in vivo bone and which is capable of easily increasing osteoblast even when a difference in strength exists. In order to solve the issues, the method for producing compressed fiber structural material 1, includes: a step of preparing biocompatible fiber 14 having an average diameter of 5 μm-50 μm and an aspect ratio of 20-500; and a step of molding compressed fiber structural material 1 by cold pressing/shearing biocompatible fiber 14, compressed fiber structural material 1 having an average pore diameter that is in the range of 60 μm-100 μm inclusive and a void fraction that is in the range of 25%-50% inclusive, both obtained by measurement in accordance with the mercury penetration method. Further, it is preferable for the cold pressing/shearing is performed by controlling a compressive pressure in the range of 200 MPa-2000 MPa, a shearing stroke length in the range of 0.2 mm-5 mm and a shearing velocity in the range of 0.5 mm/min-5 mm/min. ## Claims ### Claim 1 A method for producing a compressed fiber structural material, comprising: a step of preparing a biocompatible fiber having an average diameter of 5 μm-50 μm and an aspect ratio of 20-500; and a step of molding a compressed fiber structural material by cold pressing/shearing the biocompatible fiber, the compressed fiber structural material having an average pore diameter that is in the range of 60 μm-100 μm inclusive and a void fraction that is in the range of 25%-50% inclusive, both obtained by measurement in accordance with the mercury penetration method, wherein a titanium fiber is used as the biocompatible fiber, and the step of molding a compressed fiber structural material includes: a step of obtaining the primary compressed compact by cold pressing/shearing the biocompatible fiber; and a step of secondary-molding the primary compressed compact that is sandwiched by the magnesium powder from the top and the bottom or that has the magnesium powder deposited on either one of the top and the bottom. ### Claim 2 (depends on 1) The method for producing a compressed fiber structural material according to claim 1, wherein the cold pressing/shearing is performed by controlling a compressive pressure in the range of 200 MPa-2000 MPa, a shearing stroke length in the range of 0.2 mm-5 mm and a shearing velocity in the range of 0.5 mm/min-5 mm/min. ### Claim 3 (depends on 1) The method for producing a compressed fiber structural material according to claim 1, wherein a bulk density of the compressed fiber structural material is controlled so as to be in the range of 3 g/cm3-5 g/cm3. ### Claim 4 A compressed fiber structural material, comprising: a biocompatible fiber having an average diameter of 5 μm-50 μm and an aspect ratio of 20-500, the biocompatible fiber being compressed and solidified without sintering, the biocompatible fiber being a titanium fiber as a compressed compact; magnesium powders deposited on at least one of the top surface and the bottom surface of the compressed compact, the magnesium powders being compressed and solidified without sintering; and an average pore diameter in the range of 60 μm-100 μm inclusive and a void fraction in the range of 25%-50% inclusive, both of the average pore diameter and the void fraction being obtained by measurement in accordance with the mercury penetration method. ### Claim 5 (depends on 4) The compressed fiber structural material according to claim 4, wherein a bulk density of the compressed fiber structural material is controlled so as to be in the range of 3 g/cm3-5 g/cm3.