Assisted conversion of biological and chemical pathway information to three-dimensional animations
AssigneeAutodesk, Inc.
InventorsSam Latif Ali, Merry Shiyu Wang, Mark Alan Templin, Christopher Jerome Andrews
Life of this patent
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Abstract
This specification relates to computer animations, and more particularly to computer animations of biological and chemical pathways in which information defining the molecular assets, interactions and sequence of events involved in the pathway is combined with graphical information to generate a three-dimensional animation of the pathway.
Claims38
A computer-implemented method for generating an animation of molecular interactions occurring in a biological or chemical pathway, comprising:
- obtaining by a processor pathway information comprising (1) information defining two or more molecular assets involved in a biological or chemical pathway, (2) information defining molecular interactions between at least two of the molecular assets, and (3) sequence information linking the information defining molecular assets and the information defining the molecular interactions so as to define a sequence of at least two events involved in the biological or chemical pathway, wherein the sequence of events includes at least one molecular interaction selected from the group consisting of molecular binding, chemical reaction, dimerizing, polymerizing, molecular dissociation, and molecular conformational change;
- obtaining or generating by a processor graphical information comprising a three-dimensional graphical representation of the structure of each of the molecular assets;
- and
- generating by a processor from the pathway information and graphical information a three-dimensional animation of the molecular interactions occurring in the biological or chemical pathway wherein the three-dimensional graphical representations of the molecular assets appear to interact in a sequence defined by the sequence information such that the animation provides an animated depiction of the at least two events involved in the biological or chemical pathway;
- providing the generated animation or a portion thereof, for display on a display device in a graphical user interface that is configured to allow a user to view or edit the animation, or both.
A system comprising:
- data processing apparatus programmed to perform operations comprising:
- obtaining pathway information comprising (1) information defining two or more molecular assets involved in a biological or chemical pathway, (2) information defining molecular interactions between at least two of the molecular assets, and (3) sequence information linking the information defining molecular assets and the information defining the molecular interactions so as to define a sequence of at least two events involved in the biological or chemical pathway, wherein the sequence of events includes at least one molecular interaction selected from the group consisting of molecular binding, chemical reaction, dimerizing, polymerizing, molecular dissociation, and molecular conformational change;
- obtaining or generating graphical information comprising a three-dimensional graphical representation of the structure of each of the molecular assets;
- generating from the pathway information and graphical information a three-dimensional animation of the molecular interactions occurring in the biological or chemical pathway wherein the three-dimensional graphical representations of the molecular assets appear to interact in a sequence defined by the sequence information such that the animation provides an animated depiction of the at least two events involved in the biological or chemical pathway;
- and
- providing the generated animation or a portion thereof, for display on a display device in a graphical user interface that is configured to allow a user to view or edit the animation, or both.
A non-transitory computer-readable medium having program instructions stored thereon that, when executed by data processing apparatus, cause the data processing apparatus to perform operations comprising:
- obtaining pathway information comprising (1) information defining two or more molecular assets involved in a biological or chemical pathway, (2) information defining molecular interactions between at least two of the molecular assets, and (3) sequence information linking the information defining molecular assets and the information defining the molecular interactions so as to define a sequence of at least two events involved in the biological or chemical pathway, wherein the sequence of events includes at least one molecular interaction selected from the group consisting of molecular binding, chemical reaction, dimerizing, polymerizing, molecular dissociation, and molecular conformational change;
- obtaining or generating graphical information comprising a three-dimensional graphical representation of the structure of each of the molecular assets;
- generating from the pathway information and graphical information a three-dimensional animation of the molecular interactions occurring in the biological or chemical pathway wherein the three-dimensional graphical representations of the molecular assets appear to interact in a sequence defined by the sequence information such that the animation provides an animated depiction of the at least two events involved in the biological or chemical pathway;
- and
- providing the generated animation or a portion thereof, for display on a display device in a graphical user interface that is configured to allow a user to view or edit the animation, or both.
Dependencies are inferred from the claim text.