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US 9,316,646 B2Granted
Anti-human ROR1 antibodies
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsChristoph Rader, Sivasubramanian Baskar
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Abstract
The invention relates to antibodies having specificity for human ROR1, compositions thereof, and methods for using such antibodies, including in the diagnosis and treatment of disorders associated with aberrant ROR1 expression.
Claims32
An antibody having specificity for the extracellular domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1), comprising complementarity determining regions (CDRs) with the following sequences:
- SEQ ID NO:
- 4, SEQ ID NO:
- 6, SEQ ID NO:
- 8, SEQ ID NO:
- 11, SEQ ID NO:
- 13, and SEQ ID NO:
- 15.
4 more elements
Dependencies are inferred from the claim text.