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US 9,316,612 B2Granted
Regenerative nanosensor devices
AssigneeYale University
InventorsMark A. Reed, Xuexin Duan, Nitin Rajan
Life of this patent
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Abstract
The present invention provides a regenerative nanosensor device for the detection of one or more analytes of interest. In certain embodiments, the device comprises a nanostructure having a reversible functionalized coating comprising a supramolecular assembly. Controllable and selective disruption of the assembly promotes desorption of at least part of the reversible functionalized coating thereby allowing for reuse of the regenerative device.
Claims12
A method of replacing a receptor molecule functionalized on a nanostructure of a regenerative nanosensor device comprising:
- providing the regenerative nanosensor device comprising the nanostructure forming an electrically conducting pathway between at least a first contact and a second contact, a nanostructure surface having a first coating comprising a reversible functionalized supramolecular assembly comprising a first receptor molecule;
- and
- disrupting the supramolecular assembly of the first coating to induce a selective removal of at least one layer of the first coating, thereby forming an unfunctionalized nanostructure.
Dependencies are inferred from the claim text.