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AssigneeThe Johns Hopkins University
InventorsBert Vogelstein, Kenneth W. Kinzler, D. Williams Parsons, Sian Jones, Scott Kern, Ralph Hruban, James R. Eshleman, Michael Goggins, Alison Klein, Manuel Hidalgo, Victor E. Velculescu
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The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient.
A method of administering a therapy to a human with a pancreatic cancer, comprising:
Dependencies are inferred from the claim text.