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US 9,315,587 B2Granted
Oligosaccharide compounds
AssigneesVictoria Link Limited, The University of Liverpool
InventorsRalf Schwoerer, Jeremy E. Turnbull, Peter Charles Tyler, Olga Vladimirovna Zubkova
Life of this patent
Estimating the term…
Abstract
The invention relates generally to oligosaccharide compounds and the use of these compounds as pharmaceuticals for treating diseases or conditions in which it is desirable to inhibit β-secretase.
Claims22
An octasaccharide, decasaccharide or dodecasaccharide compound of the formula (I):
- H-Q-V-W-X-Y-Z-A (I)
- where:
- A is an optionally substituted alkoxy, aralkoxy, aryloxy group;
- W, X, Y and Z are each independently a disaccharide of formula (i);
- V is a disaccharide of formula (i) or V is absent;
- and
- Q is a disaccharide of formula (i) or Q is absent
- where:
- R1 is SO3H;
- R2 is H;
- R3 is acyl;
- R4 is H or SO3H;
- and
- each R5 and R6 is independently selected from COOH and H;
- provided that one of R5 and R6 in each disaccharide is H and the other is COOH;
- and provided that all R3 groups in the octasaccharide, decasaccharide or dodecasaccharide are the same as each other and provided that all R4 groups in the octasaccharide, decasaccharide or dodecasaccharide are the same as each other;
- or a pharmaceutically acceptable salt thereof.
14 more elements
Dependencies are inferred from the claim text.