Benzimidazole derivatives and their pharmaceutical compositions and uses
AssigneeXuanzhu Pharma Co., Ltd.
InventorsZhenhua Huang, Guanglian Zhou
Life of this patent
Estimating the term…
Abstract
The present invention relates to benzimidazole derivatives and their pharmaceutical compositions and uses, specifically to benzimidazole derivatives of Formula (I), or their stereoisomer, pharmaceutically acceptable salt or solvates thereof, in which R1, R2, R3, R4, R5 and n have the definitions in the description; the present invention further relates to a pharmaceutical composition containing the compounds, methods for preparing the compounds, and use of the compounds for manufacturing of a medicament for prophylaxis and/or treatment of peptic ulcer, ulcer hemorrhage and diseases associated with gastric acid.
Claims13
A compound of Formula (I), or a stereoisomer, solvate or pharmaceutically acceptable salt thereof:
- wherein,
- R1, R2 and R3 are independently hydrogen atom, C1-4 alkyl, C1-4 alkoxyl, C1-4alkoxyl-C1-4 alkyl, C1-4alkoxyl-C1-4 alkoxyl, haloC1-4 alkyl or halo C1-4 alkoxyl;
- R4 is hydrogen atom;
- R5 represents formula
- R6 and R7 are independently a hydrogen atom;
- Ring A is a 5-membered ring having one oxygen atom;
- Ring B is a 5-membered ring having one oxygen atom;
- and
- n is 1 or 2.
Dependencies are inferred from the claim text.