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US 9,315,483 B2Granted
Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
AssigneeConcert Pharmaceuticals, Inc.
InventorsAndrew D. Jones, Robert E. Zelle, I. Robert Silverman
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Abstract
The present invention provides a convenient and efficient process for the synthesis of d2-benzo[d][1,3]dioxoles.
Claims2
A compound represented by the following structural formula:
- wherein:
- the isotopic enrichment of the compound with deuterium is at least 99.0%;
- n is 1, 2 or 3;
- each R1 is independently —ORa or —CHO;
- and
- Ra is —H or a phenol protecting group.
3 more elements
Dependencies are inferred from the claim text.