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US 9,315,447 B2Granted
Compositions and methods for the treatment of inflammation
AssigneeA.T. Resolve Sarl
InventorsPer Gjorstrup, C. Eric Schwartz
Life of this patent
Estimating the term…
Abstract
The invention relates to novel resolvin compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel resolvin compounds of the invention.
Claims16
A pharmaceutical preparation suitable for treating or preventing an ophthalmic condition in a human patient, said preparation comprising:
- one or more of:
- a compound of any of formulae I-IX,
- a compound of formula A,
- a compound of any one of formulae 1-49,
- a lipoxin compound, or
- an oxylipin compound, and
- one or more pharmaceutically acceptable excipients,
- wherein the pharmaceutical preparation is characterized in that
- a) the one or more of a compound of any of formulae I-IX, a compound of formula A, a compound of any one of formulae 1-49, a lipoxin compound, or an oxylipin compound is present in a concentration over 90 micromolar,
- b) the pharmaceutical preparation is a solution with a pH in the range of 5.5 to 7.4, and/or
- c) the pharmaceutical preparation further comprises one or more surfactants.
8 more elements
A method of treating or preventing an ophthalmic condition comprising administering a pharmaceutical preparation comprising:
- one or more of:
- a compound of any of formulae I-IX,
- a compound of formula A,
- a compound of any one of formulae 1-49,
- a lipoxin compound, or
- an oxylipin compound, and
- one or more pharmaceutically acceptable excipients,
- wherein the pharmaceutical preparation is characterized in that
- a) the one or more of a compound of any of formulae I-IX, a compound of formula A, a compound of any one of formulae 1-49, a lipoxin compound, or an oxylipin compound is present in a concentration over 90 micromolar,
- b) the pharmaceutical preparation is a solution with a pH in the range of 5.5 to 7.4, and/or
- c) the pharmaceutical preparation further comprises one or more surfactants
8 more elements
A packaged pharmaceutical for delivering eyedrops to an eye in need of treatment for an opthalmic condition, wherein the eyedrops comprise a
- a pharmaceutical preparation comprising:
- one or more of:
- a compound of any of formulae I-IX,
- a compound of formula A,
- a compound of any one of formulae 1-49,
- a lipoxin compound, or
- an oxylipin compound, and
- one or more pharmaceutically acceptable excipients,
- wherein the pharmaceutical preparation is characterized in that
- a) the one or more of a compound of any of formulae I-IX, a compound of formula A, a compound of any one of formulae 1-49, a lipoxin compound, or an oxylipin compound is present in a concentration over 90 micromolar,
- b) the pharmaceutical preparation is a solution with a pH in the range of 5.5 to 7.4, and/or
- c) the pharmaceutical preparation further comprises one or more surfactants.
9 more elements
Dependencies are inferred from the claim text.