Method for controlling an electroporation device

An electroporation device comprising:

• a plurality of pairs of electrodes;
• a power supply for providing an electrical power signal;
• and
• an electronic control unit connected to the electrodes and the power supply to apply the electrical power signal as an electroporation treatment to at least one pair of the plurality of electrodes, the electronic control unit configured to perform a method comprising:
• detecting, in the course of an electroporation treatment, a condition of malfunctioning or fail for one or more pairs of electrodes for which at least one electrical parameter of the power signal supplied to the one or more pairs of electrodes has an anomalous value;
• storing an indicator of the one or more pairs of electrodes in the fail condition;
• and
• selecting the one or more pairs of electrodes in the fail condition and re-computing for each of the one or more pairs, new parameters for implementing a subsequent electroporation process, wherein re-computing the new parameters comprises:
• re-applying said power signal to said one or more pairs of electrodes in the fail condition,
• verifying the value of the current thus supplied to the one or more pairs of electrodes,
• when said current is lower than a given threshold, calculating a voltage value configured for enabling an increase of the current to bring the current to a target value and comparing said voltage value with a threshold value, and
• when the voltage value is lower than the threshold value, storing said voltage value as a new electroporation parameter, and
• when the voltage value is not lower than the threshold value, adopting one or more corrective actions.