US 9,314,572 B2 · Controlling drug delivery transitions

Abstract

Devices, systems, and techniques for transitioning between different drug delivery sources or different drug concentrations may account for diffusion and mixing of drug within the fluid. In one example, a method may include determining a flow rate for a fluid to be delivered to a patient via a drug pump and a catheter in fluid communication with a reservoir of the drug pump. The fluid includes a drug. The method also includes determining a concentration profile of the drug delivered via the catheter, wherein the concentration profile identifies a volume of delivered fluid needed to achieve a target transition dose of the drug. The method further includes determining, by a processor and based on the flow rate and the concentration profile, an initial delivery period required to achieve the target transition dose by delivering the fluid at the flow rate.

Claims24

Dependent claims

A method comprising:

determining a flow rate for a fluid to be delivered to a patient via a drug pump and a catheter in fluid communication with a reservoir of the drug pump, wherein the fluid comprises a therapeutic agent;
determining a concentration profile of the therapeutic agent delivered via the catheter, wherein the concentration profile represents a gradient of different concentrations of the therapeutic agent along a length of the catheter and identifies a volume of the fluid deliverable by the drug pump and needed to achieve a target transition dose of the therapeutic agent;
and
determining, by a processor and based on the flow rate and the concentration profile, an initial delivery period required to achieve the target transition dose by delivering the fluid at the flow rate.

1 more element

A system comprising:

one or more processors configured to:
determine a flow rate for a fluid to be delivered to a patient via a drug pump and a catheter in fluid communication with a reservoir of the drug pump, wherein the fluid comprises a therapeutic agent;
determine a concentration profile of the therapeutic agent delivered via the catheter, wherein the concentration profile represents a gradient of different concentrations of the therapeutic agent along a length of the catheter and identifies a volume of the fluid deliverable by the drug pump and needed to achieve a target transition dose of the therapeutic agent;
and
determine, based on the flow rate and the concentration profile, an initial delivery period required to achieve the target transition dose by delivering the fluid at the flow rate.

2 more elements

Dependencies are inferred from the claim text.

Controlling drug delivery transitions

Life of this patent

Controlling drug delivery transitions

Life of this patent

Abstract

Claims24