Nanostructured surfaces for biomedical/biomaterial applications and processes thereof

A system for fabricating nano-structures for medical applications, the system comprising:

• a mold having a first surface defining nano-structures for molding articles therefrom,
• wherein the nano-structures are less than 500 nm in a dimension,
• wherein the mold comprises an oligomer produced from polymerization of monomers selected from the group consisting of trifluorochloroethylene, trifluoroethylene, hexafluoro-iso-propyl (meth)acrylate, 1H,1H,3H-hexafluorobutyl(meth)acrylate, 1H,1H,5H-octafluoropentyl (meth)acrylate, pentafluorophenyl (meth)acrylate, perfluoro(methyl vinyl ether), 1,1-dihydroperfluorobutyl (meth)acrylate, and combinations thereof, and a functional monomer included in the polymerization of the oligomer, wherein the functional monomer is selected from the group consisting of hydroxyethyl(meth)acrylate, (meth)acrylic acid, vinyl acetate, vinyl sulfonic acid, styrene sulfonic acid, 4-hydroxy styrene, 2-acrylamido-2-methyl propane sulfonate, maleic anhydride, glycidyl methacrylate, isocyanatoethyl methacrylate, and combinations thereof;
• and
• a biomaterial configured to be molded by the mold and form a medical article that treats or prevents a biologic tissue or condition.