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US 9,314,545 B2Granted
Minimally invasive treatment of vertebra (MITV) using a calcium phosphate combination bone cement
AssigneeLife Science Enterprises, Inc.
InventorsAliassghar N. Tofighi, Aron D. Rosenberg, Tak Lung Chang, Michael Strunk
Life of this patent
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Abstract
Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.
Claims16
A method for performing vertebroplasty on a vertebral body comprising:
- a) injecting a flowable bone cement into at least one said vertebral body, said flowable bone cement comprising a nanocrystalline apatitic calcium phosphate, a radio-opaque agent, and a pharmaceutically acceptable fluid in an amount sufficient to produce said flowable bone cement, wherein said nanocrystalline apatitic calcium phosphate comprises crystals having a domain size within the range of 30-80 nm;
- and
- b) allowing said flowable bone cement to harden, wherein said flowable bone cement, when hardened, has a compressive strength of 1 MPa or greater and is resorbable in vivo.
Dependencies are inferred from the claim text.