Treatment of mammalian physiological reaction of IgE antibodies present in said mammal upon contact with the corresponding antigen
OwnerIra Sandersinventor
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Abstract
A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of therapeutically effective amount of a neurotoxin (CnT) derived from Clostridia sp.
Claims20
A method of preventing allergen triggered asthma comprising administering a therapeutically effective amount of a neurotoxin into the sphenopalatine ganglia of a mammal at risk for suffering from asthma to prevent allergen triggered asthma, wherein the neurotoxin is isolated or purified from a species of Clostridia selected from the group consisting of C. botulinum, C. butyricum, C. beratti, and C. Tetani.
A method of preventing of allergen triggered asthma comprising administering a therapeutically effective amount of a neurotoxin into the nasal mucosa of a mammal at risk for suffering from asthma to prevent allergen triggered asthma, wherein the neurotoxin is isolated or purified from a species of Clostridia selected from the group consisting of C. botulinum, C. butyricum, C. beratti, and C. tetani.
Dependencies are inferred from the claim text.