Insoluble dietary fiber-containing product derived from grain seeds
AssigneeKirin Holdings Kabushiki Kaisha
InventorsHideo Ohmae, Hiroshi Murayama, Naohiro Takimoto, Yuji Sakamoto, Osamu Kanauchi, Mikio Katayama, Hiroyuki Watanabe, Yuta Komano
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Abstract
This invention provides a product safe for treating, improving or preventing an inflammatory bowel disease such as ulcerative colitis, and provides a product comprising an insoluble dietary fiber obtained by enzymatic treatment of seeds of a grain plant(s) or germinated young seeds thereof, as well as a food or drink or medicament comprising the product.
Claims22
A method for the treatment or prevention of ulcerative colitis, said method comprising administering a therapeutically-effective amount of an insoluble dietary fiber-containing product to a subject in need thereof, wherein the insoluble dietary fiber-containing product has 90% or more of the aleurone layer removed and wherein said product is derived from seeds of a Gramineae plant(s) and produced by a process comprising the following steps of:
- (a) preparing a raw-material by pulverizing or polishing the seeds of the Gramineae plant(s) then recovering the obtained outer fraction of the seeds;
- (b) subjecting the raw material to a starch removing treatment to prepare a starch free fraction;
- (c) enzymatically treating the fraction prepared in the step (b) with an enzyme having hemicellulase activity;
- and
- (d) recovering the insoluble fraction containing insoluble dietary fibers from the enzymatically treated fraction produced by step (c).
A method for suppressing diarrhea resulting from ulcerative colitis, said method comprising administering a therapeutically-effective amount of an insoluble dietary fiber-containing product to a subject in need thereof, wherein the insoluble dietary fiber-containing product has 90% or more of the aleurone layer removed and wherein said product is derived from seeds of a Gramineae plant(s) and produced by a process comprising the following steps of:
- (a) preparing a raw-material by pulverizing or polishing the seeds of the Gramineae plant(s) then recovering the obtained outer fraction of the seeds;
- (b) subjecting the raw material to a starch removing treatment to prepare a starch free fraction;
- (c) enzymatically treating the fraction prepared in the step (b) with an enzyme having hemicellulase activity;
- and
- (d) recovering the insoluble fraction containing insoluble dietary fibers from the enzymatically treated fraction produced by step (c).
A method for reducing damage to the intestine mucosa resulting from ulcerative colitis, said method comprising administering a therapeutically-effective amount of an insoluble dietary fiber-containing product to a subject in need thereof, wherein the insoluble dietary fiber-containing product has 90% or more of the aleurone layer removed and wherein said product is derived from seeds of a Gramineae plant(s) and produced by a process comprising the following steps of:
- (a) preparing a raw-material by pulverizing or polishing the seeds of the Gramineae plant(s) then recovering the obtained outer fraction of the seeds;
- (b) subjecting the raw material to a starch removing treatment to prepare a starch free fraction;
- (c) enzymatically treating the fraction prepared in the step (b) with an enzyme having hemicellulase activity;
- and
- (d) recovering the insoluble fraction containing insoluble dietary fibers from the enzymatically treated fraction produced by step (c).
Dependencies are inferred from the claim text.