Biological effects of compositions of rosmarinic acid
AssigneesNestec S.A., L'oreal
InventorsVanessa Crespy, Isabelle Castiel, Rachid Bel-Rhlid, Nicolas Page, Thomas Raab
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Abstract
The present invention relates to compositions of rosmarinic acid or its derivatives and to the use of a hydrolytic enzyme or of microorganism containing or producing hydrolytic enzymes in these compositions. The invention also pertains to methods for improving the biological effects of the rosemary extracts and for administering such compositions to a human or animal subject for improving the skin, coat, hair or health of the subject.
Claims14
A composition formulated for oral administration and comprising a bioefficiency enhancing agent consisting of rosmarinic acid in combination with a hydrolysis effective amount of a hydrolytic enzyme selected from chlorogenate esterase or a microorganism containing or producing a hydrolytic enzyme of an esterase;
- wherein the microorganism is selected from the group consisting of Lactobacillus johnsonii (CNCM 1-1225), Bifidobacterium longum (ATCC BAA-999), Bifidobacterium lactis (CNCM 1-3446) and mixtures thereof;
- so that the rosmarinic acid is hydrolysed into caffeic acid and 3,4-dihydroxy phenyllactic acid in amounts sufficient to enhance the bioefficiency of the composition after consumption compared to non-hydrolysed rosmarinic acid containing compositions, wherein the microorganism is a probiotic and is present in an amount ranging from 1×103 to 1×108 cfu/g.
Dependencies are inferred from the claim text.