Oral and injectable formulations of tetracycline compounds
AssigneeParatek Pharmaceuticals, Inc.
InventorSean Johnston
Life of this patent
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Abstract
Injectable and oral formulations of a tetracycline compound are described. In one embodiment, the invention pertains to an oral formulation of a 9-aminomethyl tetracycline compound, or a salt thereof, in tablet form or capsule. The formulations may be used, for example, to treat infections.
Claims22
An oral formulation in tablet form, comprising about 19% to about 22% weight percent of 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, a diluent, a stabilizer, a glidant, a lubricant, and a disintegrant, wherein the oral formulation is compressed using roller compaction.
An oral formulation in tablet form, comprising about 19% to about 22% weight percent of 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline tosylate salt, lactose, microcrystalline cellulose, sodium bisulfite, colloidal silicon dioxide, sodium stearyl fumarate and crosspovidone, wherein the oral formulation is compressed using roller compaction.
Dependencies are inferred from the claim text.