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US 9,314,474 B2Granted
Formulations of 14-epi-analogues of vitamin D
AssigneeHybrigenics
InventorRemi Delansorne
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Abstract
The present invention provides new formulations of 14-epi-analogues of vitamin D, such as inecalcitol, providing improved absorption profile.
Claims35
An oral formulation wherein said formulation is a dry formulation which comprises:
- at least one 14-epi-analogue of vitamin D in a concentration of between 0.001 and 50% (weight),
- carboxymethylcellulose in a concentration between 0.1% and 50% (weight), and
- one or more optional pharmaceutically acceptable excipient(s)
- wherein said 14-epi-analogue of vitamin D is inecalcitol and wherein the formulation is characterized by an improved absorption profile over the medium chain triglycerides formulation of said 14-epi-analogue of vitamin D.
1 more element
Dependencies are inferred from the claim text.