Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
AssigneeVertex Pharmaceuticals Incorporated
InventorsAli Keshavarz-Shokri, Beili Zhang, Mariusz Krawiec
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Abstract
The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith.
Claims37
A solid form of 3-(6-(I-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1), characterized as Compound 1, Solvate Form A.
Compound 1, Solvate Form A, wherein Compound 1, Solvate Form A has a particle size D50 of 2.0 microns.
Dependencies are inferred from the claim text.