Combination therapy
AssigneeDimerix Bioscience Pty Ltd.
InventorsKevin D. G. Pfleger, Elizabeth McCall, James Williams
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AssigneeDimerix Bioscience Pty Ltd.
InventorsKevin D. G. Pfleger, Elizabeth McCall, James Williams
Estimating the term…
The invention relates to pharmaceutical compositions comprising: (a) at least one angiotensin receptor blocker or a pharmaceutically acceptable salt thereof, and (b) at least one chemokine receptor pathway inhibitor or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising: (a) at least one angiotensin receptor blocker or a pharmaceutically acceptable salt thereof; and (b) at least one chemokine receptor pathway inhibitor or a pharmaceutically acceptable salt thereof which inhibits a component of the chemokine receptor pathway other than the chemokine receptor. Oral sustained release pharmaceutical compositions comprising the pharmaceutical composition, as well as injectable sustained release pharmaceutical compositions comprising the pharmaceutical composition are described. The invention further relates to tablets, capsules, injectable suspensions, and compositions for pulmonary or nasal delivery comprising the pharmaceutical composition. Also described are: methods for assessing the efficacy of the pharmaceutical composition; methods for assessing the inhibition or partial inhibition activity of the pharmaceutical composition; methods for the treatment, amelioration or prevention of a condition or disease comprising administering to a subject a therapeutically effective amount of the pharmaceutical composition; and the use of the pharmaceutical composition for the manufacture of a dosage form for the treatment of a disease.
A method for the treatment or amelioration of a condition or disease comprising:
A method of treating kidney disease in a patient in need thereof, said method comprising administering to the subject a therapeutically effective amount of a CCR2 inhibitor concurrently or sequentially with an ATIR blocker.
Dependencies are inferred from the claim text.