Stable formulations of antiplatelet agents, omega-3 fatty acids and amylose in soft gelatin capsules

A formulation consisting capsules consisting of

• shell and
• filling composition,
• said shell consisting of gelatin, amylose or starch containing between 50% and 70% amylose and anhydrous citric acid in percentages ranging from 1% to 30%
• said filling consisting of acetylsalicylic acid or a pharmaceutically acceptable salt thereof, omega-3 fatty acids or esters thereof, an organic acid in percentages ranging from 1% to 30% and amylose or a starch containing between 50% and 70% amylose.

A formulation consisting of capsules consisting of

• shell and
• filling composition,
• said shell consisting of gelatin, an organic acid and amylose or starch containing between 50% and 70% amylose;
• said filling composition consisting of acetylsalicylic acid or a pharmaceutically acceptable salt thereof, omega-3 fatty acids or esters thereof, an organic acid, amylose or a starch containing between 50% and 70% amylose, and an oil suspension of crystals and pellets.

A formulation consisting of capsules consisting of

• shell and
• filling composition,
• said shell consisting of gelatin, and amylose or starch containing between 50% and 70% amylose;
• said filling composition consisting of acetylsalicylic acid or a pharmaceutically acceptable salt thereof, omega-3 fatty acids or esters thereof and an organic acid.

A formulation consisting of capsules consisting of

• shell and
• filling composition,
• said shell consisting of gelatin, an organic acid and amylose or starch containing between 50% and 70% amylose;
• said filling composition consisting of acetylsalicylic acid or a pharmaceutically acceptable salt thereof, omega-3 fatty acids or esters thereof, an organic acid, and an oil suspension of crystals and pellets.