Functionalized fullerenes as antifungal agents
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsVijay Krishna, Brij M. Moudgil, Benjamin L. Koopman
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Abstract
Functionalized fullerenes are used in a method of combating fungal growth on surfaces and treating fungal diseases of patients. Surfaces that can be treated by the materials comprising an effective amount of functionalized fullerenes include those of fruits, vegetables, harvested grains, plants, or plant seeds. The method of combating fungal growth on a surface can be augmented but is not dependent on irradiation of the surface by light. Functional fullerenes are employed in various dosage forms such as topical, ingestible or administration.
Claims11
A method of reducing mold and mildew growth characterized by growth of Aspergillus Niger on a surface, comprising the steps of:
- providing a material comprising an effective amount of functionalized fullerenes, wherein said functionalized fullerenes consist of fullerenes (Cx where x is 20 to 1500) attached to at least one functional group at one to a majority of the carbons in the fullerene, wherein said functional groups are selected from the group consisting of OH, Br, H, Gd, Ti, and C(COOH)2, and wherein at least one of the functional groups is OH;
- and
- distributing said material comprising functionalized fullerenes over the surface, wherein said material reduces mold or mildew growth in the dark.
A method of treating a fungal disease characterized by growth of Aspergillus Niger in a patient, comprising the steps of:
- providing a material comprising an effective amount of functionalized fullerenes, wherein said functionalized fullerenes consist of fullerenes (Cx where x is 20 to 1500) attached to at least one functional group at one to a majority of the carbons in the fullerene, wherein said functional groups are selected from the group consisting of OH, Br, H, Gd, Ti, and C(COOH)2, and wherein at least one of the functional groups is OH;
- and
- administering said material to the patient, wherein said material reduces mold or mildew growth in the dark.
Dependencies are inferred from the claim text.