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US 9,310,367 B2Granted
Compositions and methods for screening for lyme disease
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsPeter D. Burbelo, Adriana Marques, Michael J. Iadarola
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Abstract
The invention provides compositions, methods, and kits for the diagnosis or detection of infection by a pathogen that causes Lyme disease in a subject.
Claims4
A method of diagnosing an infection by Borrelia sp. in a subject comprising:
- a) obtaining a sample from a subject,
- b) contacting the sample with a composition comprising an isolated peptide, wherein said isolated peptide comprises SEQ ID NO:
- 1, and
- c) detecting binding of the isolated peptide to an antibody in the sample, wherein the binding between the peptide and the antibody is indicative that the subject has an infection with a Borrelia sp.,
- wherein the Borrelia sp. is selected from B. burgdorferii, B. garinii and B. afzelii.
2 more elements
Dependencies are inferred from the claim text.