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US 9,309,313 B2Granted
Therapeutic compositions for treatment of ocular inflammatory disorders
AssigneeThe Schepens Eye Research Institute, Inc.
InventorsReza Dana, Sunil Chauhan
Life of this patent
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Abstract
The invention comprises a composition with means to inhibit the function of the inflammatory cytokine IL-17 and methods for using this composition to treat IL-17-mediated ocular inflammatory disorders. The invention also discloses devices for delivering this composition to the eye.
Claims10
A method for reducing the severity of dry eye syndrome comprising
- identifying a subject characterized as suffering from dry eye syndrome;
- topically administering directly to an eye of a subject a composition that inhibits binding of an inflammatory interleukin-17 (IL-17) cytokine to an IL-17 receptor;
- and
- inhibiting or reducing eye dryness associated with said dry eye syndrome, thereby reducing the severity of said dry eye syndrome, wherein said dry eye syndrome is a non-Sjogren's syndrome associated dry eye syndrome associated with meibomian gland dysfunction, and is not uveitis, intraocular conditions, or inflammation of interior tissues of the eye.
1 more element
Dependencies are inferred from the claim text.