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US 9,309,260 B2Granted
Inhibitors of hepatitis C virus
AssigneePresidio Pharmaceuticals, Inc.
InventorsMin Zhong, Leping Li
Life of this patent
Estimating the term…
Abstract
A class of compounds that inhibit Hepatitis C Virus (HCV) is disclosed, along with compositions containing the compound, and methods of using the composition for treating individuals infected with HCV.
Claims10
A compound having the structure:
- wherein:
- is selected from the group consisting of
- R1 is selected from the group consisting of hydrogen, halide, —CF3, —CN, —C(O)H, —C(O)OR6—, —C(O)NHR7, —C(O)N(OH)R7, —C(═NOMe)NHR7, C(═NOH)NHR7, —CH(CF3)NHR8, —CH(CN)NHR9, —S(O)2NHR10, —C(═NCN)NHR11,
- R2 is substituted or unsubstituted aryl or heteroaryl;
- R6 is selected from the group consisting of hydrogen, allyl, C1-4 alkyl, cyclopropyl, and benzyl;
- R7 is selected from the group consisting of hydrogen, C1-4 alkyl, cyclopropyl, C1-4 alkoxy, cyclopropoxy, alkylsulfonyl, and cycloalkylsulfonyl;
- R8, R9, R10 and R11 are each independently selected from the group consisting of hydrogen, C1-4 alkyl, cyclopropyl, C1-4 alkoxy, and cyclopropoxy;
- and
- R17 is selected from the group consisting of H, F, Cl and CN;
- or a pharmaceutically acceptable salt thereof.
7 more elements
Dependencies are inferred from the claim text.