Process for preparation of dicyanocarboxylate derivatives
OwnerKeki Hormusji Ghardainventor
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Abstract
The present disclosure provides a process for preparing 2,3-dicyanopropionic acid ester of formula (I); said process comprising the following steps: i) treating an alkali metal cyanide dissolved in a solvent with a solution of 2-cyano-2-propenoic acid ester of formula (II) at a temperature ranging between 0° C. and 50° C. for a time period ranging between 2 hours and 15 hours followed by cooling below 20° C. to obtain a sodium salt of 2,3-dicyanopropionic acid ester of formula (I); and ii) neutralizing the sodium salt of 2,3-dicyanopropionic acid ester using a neutralizing agent to obtain a 2,3-dicyanopropionic acid ester of formula (I).
Claims9
A process for preparing 2,3-dicyanopropionic acid ester of formula (I);
- said process comprising the following steps:
- i) providing a slurry of sodium cyanide in a solvent and reacting with a solution of 2-cyano-2-propenoic acid ester of formula (II) which is pre-stabilized using a stabilizing agent at a temperature ranging between 0° C. and 50° C. for a time period ranging between 2 hours and 15 hours followed by cooling below 20° C. to obtain a sodium salt of 2,3-dicyanopropionic acid ester of formula (I);
- wherein, R is selected from the group consisting of C1-C4 straight or branched chain alkyl substituents and substituted or unsubstituted aromatic substituents;
- and
- R1 and R2 are hydrogen,
- ii) neutralizing the sodium salt of 2,3-dicyanopropionic acid ester using a neutralizing agent to obtain a 2,3-dicyanopropionic acid ester of formula (I),
- wherein, R is selected from the group consisting of C1-C4 straight or branched chain alkyl substituents and substituted or unsubstituted aromatic substituents;
- R1 and R2 are hydrogen;
- and
- R3 is hydrogen.
Dependencies are inferred from the claim text.