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US 9,308,295 B2Granted
Oxygenated demineralized bone matrix for bone growth
AssigneeTheracell, Inc.
InventorsAndrew J. Carter, Nelson L. Scarborough, Richard K. Grant, Frank M. Phillips, Stephen H. Hochschuler
Life of this patent
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Abstract
An improved composition for inducing bone growth is provided that is a mixture of DBM and a perfluorocarbon oxygen carrier. Injection/implantation of a composition of DBM and a perfluorocarbon results in enhancement of bone formation.
Claims19
A non-emulsified composition, consisting of:
- demineralized bone matrix (DBM) powder, granules and/or fibers coated with a perfluorocarbon;
- and
- optionally consisting of a handling agent selected from the group consisting of saline, glycerols, polyoxamers, lecithins, and combinations thereof.
A method of making a non-emulsified composition for bone growth, the method consisting of:
- coating a perfluorocarbon on DBM powder, granules, and/or fibers to form a non-emulsified mixture;
- and
- optionally adding a handling agent to the non-emulsified mixture, the handling agent being selected from the group consisting of saline, glycerols, polyoxamers, lecithins, and combinations thereof.
Dependencies are inferred from the claim text.