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US 9,308,292 B2Granted
Formable and settable polymer bone composite and methods of production thereof
AssigneeWarsaw Orthopedic, Inc.
InventorsJohn Winterbottom, David Kaes
Life of this patent
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Abstract
A composite osteoimplant. The osteoimplant includes a polymer and bone-derived particles. The composite is adapted and constructed to be formable during or immediately prior to implantation and to be set after final surgical placement.
Claims22
A method of preparing an osteoimplant, comprising:
- forming a composite comprising bone-derived particles and a polymer into a predetermined shape, the composite being manipulated into the predetermined shape at a temperature greater than about 40° C., the polymer comprising starch poly(caprolactone), poly(caprolactone), poly(l-lactide), poly(dl-lactide-co-glycolide), poly(l-lactide-co-dl-lactide), enantiomers thereof, copolymers thereof, and/or mixtures thereof, wherein the bone-derived particles are about 50% to about 75% by weight of the composite and the bone-derived particles have a size between about 50 μm and about 1 mm;
- and
- causing the polymer to set.
Dependencies are inferred from the claim text.