Method for treatment of post operative cognitive dysfunction
AssigneeImperial Innovations Limited
InventorsMervyn Maze, Marc Feldman, Niccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman
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Abstract
The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
Claims5
A method for the treatment or prophylaxis of post operative cognitive dysfunction (POCD) in a patient following surgery in said patient, the method comprising administering a therapeutically effective amount of an anti-Tumour Necrosis Factor alpha (anti-TNFα) antibody and a therapeutically effective amount of an Interleukin 1 (IL-1) receptor antagonist to said patient.
Dependencies are inferred from the claim text.