Skin compositions and methods of use thereof
AssigneeOlivo Laboratories, LLC
InventorsBetty Yu, Joseph Lomakin, Soo-Young Kang, Benjamin W. Adams
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Abstract
The present invention provides durable, natural looking, non-invasive compositions that exhibit desired aesthetic qualities. Specifically, the compositions can be used for therapeutic treatments, including treatments of wounds and headaches. The invention pertains, at least in part, to therapeutic formulations for application to the skin that comprise a) a reactive reinforcing component; and b) a cross-linking component; in which the cross-linking component facilitates in situ formation of a film over the skin.
Claims38
A therapeutic formulation for the formation of a film over the skin of a subject, comprising:
- a) a reactive reinforcing component comprising
- (i) a reactive constituent comprising as ingredients at least one vinyl functionalized organopolysiloxane and at least one hydride functionalized polysiloxane, wherein said reactive reinforcing component has a molar ratio of vinyl to hydride functional groups of about 1:10 to about 1:100, and
- (ii) a reinforcing constituent;
- and
- b) a cross-linking component;
- wherein after said cross-linking component is contacted with the reactive reinforcing component, a filmed is formed in situ on said skin.
A method for treating wounds, comprising applying to a wound on a subject a formulation comprising:
- a) a reactive reinforcing component comprising
- (i) a reactive constituent comprising as ingredients at least one vinyl functionalized organopolysiloxane and at least one hydride functionalized polysiloxane, wherein said reactive reinforcing component has a molar ratio of vinyl to hydride functional groups of about 1:10 to about 1:100, and
- (ii) a reinforcing constituent;
- and
- b) a cross-linking component;
- wherein after said cross-linking component is contacted with the reactive reinforcing component, a film is formed in situ on said wound, thereby treating the wound.
A method for delivering an agent to a subject, comprising applying to the subject's skin a formulation comprising:
- a) a reactive reinforcing component comprising
- (i) a reactive constituent comprising as ingredients at least one vinyl functionalized organopolysiloxane and at least one hydride functionalized polysiloxane, wherein said reactive reinforcing component has a molar ratio of vinyl to hydride functional groups of about 1:10 to about 1:100,
- (ii) a reinforcing constituent, and
- (iii) optionally one or more agents;
- and
- b) a cross-linking component optionally comprising one or more agents;
- wherein after said cross-linking component is contacted with the reactive reinforcing component, a film is formed in situ on said skin, thereby delivering the agent to the subject;
- wherein the one or more agents is present in at least a) or b).
A method of treating a stress headache in a subject comprising applying to an appropriate area of the subject's skin a formulation in an amount effective to lift the subject's brow, the formulation comprising
- a) a reactive reinforcing component comprising
- (i) a reactive constituent comprising as ingredients at least one vinyl functionalized organopolysiloxane and at least one hydride functionalized polysiloxane, wherein said reactive reinforcing component has a molar ratio of vinyl to hydride functional groups of about 1:10 to about 1:100, and
- (ii) a reinforcing constituent;
- and
- b) a cross-linking component;
- wherein after said cross-linking component is contacted with the reactive reinforcing component, a film is formed in situ on said skin, thereby treating the stress headache by lifting the brow.
Dependencies are inferred from the claim text.