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AssigneeMitotech SA
InventorsVladimir P. Skulachev, Maxim V. Skulachev
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The invention relates to biology and medicine, in particular, can be used in medicine for preparation of a pharmaceutical composition for specific, self-regulating uncoupling of mitochondria. The invention may be useful in treatment of diseases and conditions associated with violation of cellular metabolism, in treatment of obesity including its pathological forms, as well as in treatment of diseases associated with increased formation of free radicals and reactive oxygen species. In addition, the invention may be used in biotechnology for stimulation of growth of yeast and microorganisms as well as for stimulation of development of tissues and organs of plant and animal origin.
A method of increasing proton permeability of a mitochondrial membrane in a cell, comprising contacting the cell with a compound of structure (1)
A method of increasing proton permeability of a mitochondrial membrane in a cell, comprising contacting the cell with a compound of structure (2)
A method of increasing proton permeability of a mitochondrial membrane in a cell, comprising contacting the cell with a compound of structure (3)
A method of increasing proton permeability of a mitochondrial membrane in a cell, comprising contacting the cell with a compound of structure (4)
A method of increasing proton permeability of a mitochondrial membrane in a cell, comprising contacting the cell with a compound of structure (5)
Dependencies are inferred from the claim text.