Method for modulating canonical Wnt pathway using folate and inositol
AssigneeUniversity of South Florida
InventorKersti K. Linask
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Abstract
The canonical Wnt signaling pathway is implicated in wound healing. Administration of a composition having myo-inositol and folic acid upregulates fibronectin and provides the greatest protection in an additive/synergistic manner against adverse Wnt/β-catenin-mediated effects on cell processes relating to cell differentiation, proliferation, and migration that relate to wound healing.
Claims10
A method of upregulating fibronectin in a wound of a patient by administering a therapeutically effective combination consisting essentially of a folate compound and an inositol compound to a patient in need thereof.
A method of treating a wound of a patient by administering a therapeutically effective combination consisting essentially of a folate compound and an inositol compound to a patient in need thereof.
A method of accelerating wound healing in a wound of a patient by administering a therapeutically effective combination consisting essentially of a folate compound and an inositol compound to a patient in need thereof.
Dependencies are inferred from the claim text.