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US 9,308,206 B2Granted
Compositions and methods for treating colon cancer
AssigneeBoard of Regents, The University of Texas System
InventorsSatish K Srivastava, Kota V Ramana
Life of this patent
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Abstract
Certain embodiments are directed to methods of treating a pathophysiological state or symptoms thereof resulting from aldose reductase-mediated signaling in a cytotoxic pathway using an aldose reductase specific inhibitor.
Claims1
A method of inhibiting colon cancer cell proliferation in a subject having colon cancer which consists of administering a pharmacologically effective amount of fidarestat which is a specific inhibitor of aldose reductase to the subject having colon cancer, wherein colon cancer cell proliferation in said subject is inhibited.
Dependencies are inferred from the claim text.