Non-aqueous taxane formulations and methods of using the same

A non-aqueous, ethanol-free docetaxel liquid formulation comprising:

• docetaxel;
• soybean oil in an amount ranging from about 1 to about 5 wt %;
• polysorbate 80 in an amount ranging from about 50 to about 60 wt %;
• polyethylene glycol in an amount ranging from about 35 to about 45 wt %;
• and
• lactic acid or lactic acid buffer in an amount ranging from 0.3 to 1 wt %;
• wherein the amount by weight of non-ionic surfactant is about equal to or greater than the amount by weight of non-aqueous solvent.

A non-aqueous, ethanol-free docetaxel liquid formulation comprising:

• docetaxel;
• a medium chain triglyceride in an amount ranging from about 1 to about 5 wt %;
• polysorbate 80 in an amount ranging from about 50 to about 60 wt %;
• polyethylene glycol in an amount ranging from about 35 to about 45 wt %;
• and
• lactic acid or lactic acid buffer in an amount ranging from 0.3 to 1 wt %;
• wherein the amount by weight of non-ionic surfactant is about equal to or greater than the amount by weight of non-aqueous solvent.