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US 9,308,186 B2Granted
Treatment of cancer with specific RXR agonists
AssigneeIo Therapeutics, Inc.
InventorRoshantha A. Chandraratna
Life of this patent
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Abstract
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR effective dose.
Claims11
A method of treating cancer, the method comprising administering to a patient in need of such treatment a retinoid X receptor (RXR) agonist at a dose which does not activate retinoic acid receptors (RAR) and wherein the dose of the RXR agonist is from about 1 to about 20 mg/m2/day, and the cancer is lung cancer;
- wherein the RXR agonist has a chemical structure
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.