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US 9,308,157 B2Granted
Whitening cosmetic
AssigneeAjinomoto Co., Inc.
InventorsYoshinobu Takino, Fumie Okura, Shinji Kuroda
Life of this patent
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Abstract
Compositions, comprising (A) a cysteine derivative represented by the formula (I) or a salt thereof: wherein X and Y are each independently OR1 or NHR2 wherein R1 and R2 are each independently a hydrogen atom or a C1-22 alkyl group; Z is a hydrogen atom or a C1-22 alkyl group; and W is a C1-22 alkyl group, a C1-22 alkoxy group or a C1-22 alkylamino group, and (B) a whitening agent, are useful for whitening skin and reducing melanin production.
Claims22
A cosmetic agent, comprising:
- (A) at least one cysteine compound represented by formula (I) or a salt thereof:
- wherein
- X and Y are each independently OR1 or NHR2 wherein R1 and R2 are each independently a hydrogen atom or a C1-22 alkyl group;
- Z is a hydrogen atom or a C 1-22 alkyl group;
- and
- W is a C1-22 alkyl group, a C1-22 alkoxy group or a C 1-22 alkylamino group;
- and
- (B) at least one whitening agent,
- wherein:
- (A) said at least one cysteine compound or a salt thereof is one or more members selected from the group consisting of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid, a salt of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid, N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2-ethyl ester, and a salt of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2-ethyl ester;
- and
- (B) said at least one whitening agent is one or more members selected from the group consisting of arbutin, cetyl ascorbyl ether, kojic acid, 4-methoxy salicylic acid, chamomilla recutita extract, ellagic acid, linoleic acid, glutathione, tranexamic acid, 4-n-butylresorcinol, and 4-hexylresorcinol.
9 more elements
A melanin production suppressive agent, comprising:
- (A) at least one cysteine compound represented by formula (I) or a salt thereof:
- wherein
- X and Y are each independently OR1 or NHR2 wherein R1 and R2 are each independently a hydrogen atom or a C1-22 alkyl group;
- Z is a hydrogen atom or a C1-22 alkyl group;
- and
- W is a C1-22 alkyl group, a C1-22 alkoxy group or a C1-22 alkylamino group;
- and
- (B) at least one whitening agent
- wherein:
- (A) said at least one cysteine compound or a salt thereof is one or more members selected from the group consisting of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid, a salt of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid, N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2-ethyl ester, and a salt of N-acetyl-2-methylthiazolidine-2,4-dicarboxylic acid 2-ethyl ester;
- and
- (B) said at least one whitening agent is one or more members selected from the group consisting of arbutin, cetyl ascorbyl ether, kojic acid, 4-methoxy salicylic acid, chamomilla recutita extract, ellagic acid, linoleic acid, glutathione, tranexamic acid, 4-n-butylresorcinol, and 4-hexylresorcinol.
9 more elements
Dependencies are inferred from the claim text.