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US 9,307,960 B2Granted
Tissue sampling devices, systems and methods
AssigneeBroncus Medical Inc.
InventorsThomas Keast, Aaron M. Weiss, Eric J. Gwerder, Jeffrey Schwardt, Edmund J. Roschak
Life of this patent
Estimating the term…
Abstract
Methods, devices, and systems are described herein that allow for improved sampling of tissue from remote sites in the body. A tissue sampling device comprises a handle allowing single hand operation. In one variation the tissue sampling device includes a blood vessel scanning means and tissue coring means to excise a histology sample from a target site free of blood vessels. The sampling device also includes an adjustable stop to control the depth of needle penetration. The sampling device may be used through a working channel of a bronchoscope.
Claims23
A tissue sampling device, configured to obtain a tissue sample in the shape of a long core, the device comprising:
- an elongate sheath having a flexibility to advance through tortuous airway anatomy;
- a shaft extending in the sheath, where the shaft and sheath are moveable relative to one another, the shaft comprising a proximal section and a distal section;
- a coring tip located at the distal section of the shaft, the coring tip having a tissue cutting distal end, and a cavity therein adapted such that the tissue cutting distal end is configured to cut and simultaneously capture the long core of the tissue sample upon axial advancement of the coring tip from the shaft through a target tissue;
- and
- a handle comprising a single-handed actuation assembly operative to advance the coring tip a pre-determined distance in an axial direction from the sheath at a velocity and force which penetrates the target tissue surface and simultaneously captures the long tissue sample core.
2 more elements
A tissue sampling system comprising:
- a tissue sampling device, the device comprising:
- an elongate sheath having a flexibility to advance through tortuous airway anatomy;
- a shaft extending in the sheath, where the shaft and sheath are moveable relative to one another, the shaft comprising a proximal section and a distal section, and a lumen extending there through;
- a coring tip located at the distal section of the shaft, the coring tip having a tissue cutting distal end, and a cavity therein adapted to cut and simultaneously capture a tissue sample shaped as a long core upon axial advancement of the coring tip from the shaft through a target tissue, the cavity being in fluid communication with the lumen;
- and
- a handle comprising a single-handed actuation assembly operative to advance the coring tip a pre-determined distance in an axial direction from the sheath at a velocity and force which penetrates the target tissue surface and simultaneously captures the tissue sample in the shape of the long core;
- and
- a syringe detachably connectable to the lumen via a fitting of the shaft.
5 more elements
A tissue sampling device, configured to obtain a tissue sample in the shape of long core, the device comprising:
- an elongate sheath having a flexibility to advance through tortuous airway anatomy;
- a shaft extending in the sheath, where the shaft and sheath are moveable relative to one another, the shaft comprising a proximal section and a distal section;
- a coring means for cutting and simultaneous capturing a tissue sample in the shape of a long core upon axial advancement of the coring tip through a target tissue;
- and
- a handle comprising a single-handed actuator for advancing the coring tip a pre-determined distance in an axial direction from the sheath at a velocity and force which penetrates the target tissue surface and captures the tissue sample in the shape of the long core.
2 more elements
A tissue sampling device, configured to obtain a tissue sample in the shape of a long core, the device comprising:
- an elongate sheath having a flexibility to advance through tortuous airway anatomy;
- a shaft extending in the sheath, where the shaft and sheath are moveable relative to one another, the shaft comprising a proximal section and a distal section, where the shaft comprises a coil extending along at least a portion of the distal section of the shaft;
- a coring tip located at the distal section of the shaft, the coring tip having a tissue cutting distal end, and a cavity therein adapted to cut and capture a long core advancement of the coring tip through a target tissue;
- and
- a handle comprising a single-handed actuation assembly operative to advance the coring tip a pre-determined distance from the sheath at a velocity and force which penetrates the target tissue surface and captures the long tissue sample core.
2 more elements
A tissue sampling system comprising:
- a tissue sampling device, the device comprising:
- an elongate sheath having a flexibility to advance through tortuous airway anatomy;
- a shaft extending in the sheath, where the shaft and sheath are moveable relative to one another, the shaft comprising a proximal section and a distal section, and a lumen extending there through;
- a coring tip located at the distal section of the shaft, the coring tip having a tissue cutting distal end, and a cavity therein adapted to cut and capture a tissue sample shaped as a long core upon advancement of the coring tip through a target tissue, the cavity being in fluid communication with the lumen;
- and
- a handle comprising a single-handed actuation assembly operative to advance the coring tip a pre-determined distance from the sheath at a velocity and force which penetrates the target tissue surface and captures the tissue sample in the shape of the long core;
- a syringe detachably connectable to the lumen via a fitting of the shaft;
- and
- a Doppler catheter extending through a lumen of the shaft.
6 more elements
A tissue sampling device, configured to obtain a tissue sample in the shape of long core, the device comprising:
- an elongate sheath having a flexibility to advance through tortuous airway anatomy;
- a shaft extending in the sheath, where the shaft and sheath are moveable relative to one another, the shaft comprising a proximal section and a distal section;
- a stiffness means for selectively adjusting the flexibility of the tissue sampling device;
- a coring means for cutting and capturing a tissue sample in the shape of a long core upon advancement of the coring tip through a target tissue;
- and
- a handle comprising a single-handed actuator for advancing the coring tip a pre-determined distance from the sheath at a velocity and force which penetrates the target tissue surface and captures the tissue sample in the shape of the long core.
3 more elements
Dependencies are inferred from the claim text.