Microorganisms having improved ornithine-producing ability and method for producing ornithine using the same
AssigneeCj Cheiljedang Corporation
InventorsHyang Choi, Kyoung Min Lee, Min Sun Kang, Sung Hoo Jhon, Hye Won Um, Su Jin Choi, Han Won Lee, Soo An Shin
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Abstract
The present invention relates to a microorganism having an improved ornithine-producing ability, in which the biosynthetic pathway of arginine form ornithine is blocked, the intracellular glutamate level is increased, and the biosynthetic pathway of ornithine from glutamate is enhanced, and a method for producing ornithine using the microorganism.
Claims8
A microorganism belonging to Corynebacterium glutamicum having an ornithine-producing ability, wherein the activities of ornithine carbamoyltransferase and a protein involved in glutamate export are modified to be attenuated, compared to their endogenous activities;
- wherein the protein involved in glutamate export has an amino acid sequence of SEQ ID NO:
- 20, or an amino acid sequence having 70% or more homology with SEQ ID NO:
- 20.
Dependencies are inferred from the claim text.