Luminescence based sensor
AssigneesDublin City University, Amic AB
InventorsJim Writser Peter Bakker, Ove Ohman, Dirk Kurzbuch, Thomas Ruckstuhl, Brian MacCraith, Stephen O'Driscoll
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Abstract
A sensor comprising a substrate (100) having a first surface (105) and a second surface (110) is described. The first surface has at least one sensor site (115) provided thereon. The substrate is configured such that on excitation of a sample provided at the sensor site, luminescence originating from the sensor site propagates into the substrate, the second surface of the substrate being configured to selectively transmit the luminescence propagating within the substrates at angles greater than the critical angle out of the substrate where it may be detected by a detector (160) provided below the substrate.
Claims20
A sensor comprising:
- a detector;
- a substrate arranged above the detector, the substrate having a first surface and a second surface parallel to the first surface and having a ring lens formed therein, the first surface having at least one sensor site provided thereon, the substrate configured such that on excitation of a sample provided at the sensor site, luminescence originating from the sensor site propagates into the substrate, the ring lens formed in the second surface of the substrate configured to selectively transmit the luminescence propagating within the substrate at angles greater than the critical angle out of the substrate;
- and
- a separate reflective optical element comprising a conical mirror being circularly symmetric when viewed along an axis passing through the at least one sensor site and which is perpendicular to the first surface and the second surface of the substrate, the conical mirror being co-operatively arranged with the substrate to provide for redirection of the transmitted light towards the detector where the transmitted light is detected, the ring lens and conical mirror being arranged relative to one another such that the light operably exits the substrate through the ring lens and is collimated by the conical mirror prior to detection by the detector,
- and wherein the second surface of the ring lens defines a recess within which a co-operable protrusion of a surface of the reflective optical element is receivable.
A sensor comprising:
- a detector;
- a substrate arranged above the detector, the substrate having a first surface and a second surface parallel to the first surface and having a ring optical element formed therein, the first surface having at least one sensor site provided thereon, the substrate being configured such that on excitation of a sample provided at the sensor site, luminescence originating from the sensor site propagates into the substrate, the ring optical element formed in the second surface of the substrate being configured to selectively transmit the luminescence propagating within the substrate at angles greater than the critical angle out of the substrate;
- and
- a reflective optical element co-operatively arranged with the substrate to provide for redirection of the transmitted light towards the detector where it is detected,
- and wherein the reflective optical element defines a paraboloidal element, the ring optical element and the reflective optical element being configured to inter-engage with one another and wherein the second surface of the ring optical element defines a recess within which a co-operable protrusion formed on a surface of the reflective optical element is receivable.
A sensor comprising:
- a first optical element comprising a substrate having a first surface and a second surface, the first surface having at least one sensor site provided thereon, the substrate configured such that on excitation of a sample provided at the sensor site, luminescence originating from the sensor site propagates into the substrate, the second surface of the substrate comprising a ring lens configured to selectively transmit the luminescence propagating within the substrate at angles greater than the critical angle out of the substrate where it is detected by a detector provided below the substrate;
- and
- a second optical element comprising a conical mirror, the second optical element being arranged relative to the first optical element to effect a reflection and collimation of light exiting the substrate towards the detector,
- and wherein the second surface of the ring lens defines a recess within which a co-operable protrusion formed on a surface of the second optical element is receivable.
A sensor comprising:
- a first optical element comprising a substrate having a first surface and a second surface, the first surface having at least one sensor site provided thereon, the substrate being configured such that on excitation of a sample provided at the sensor site, luminescence originating from the sensor site propagates into the substrate, the second surface of the substrate being configured to selectively transmit the luminescence propagating within the substrate at angles greater than the critical angle out of the substrate where it is detected by a detector provided below the substrate;
- and
- a second optical element defining a paraboloidal element, the first and second optical elements being configured to inter-engage with one another, the second optical element being arranged relative to the first optical element to effect a reflection and collimation of light exiting the substrate towards the detector and wherein the second surface of the first optical element defines a recess within which a co-operable protrusion formed on a surface of the second optical element is receivable.
Dependencies are inferred from the claim text.