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US 9,290,810 B2Granted
DNA tagged microparticles
AssigneeLawrence Livermore National Security, LLC
InventorsGeorge R. Farquar, Roald N. Leif, Elizabeth Wheeler
Life of this patent
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Abstract
In one embodiment, a product includes a plurality of particles, each particle including: a carrier that includes a non-toxic material; and at least one DNA barcode coupled to the carrier, where the particles each have a diameter in a range from about 1 nanometer to about 100 microns.
Claims16
A product, comprising
- a plurality of particles, each particle comprising:
- a carrier comprising a non-toxic material;
- and
- at least one DNA barcode coupled to the carrier,
- wherein the particles each have a diameter in a range from about 1 nanometer to about 100 microns,
- wherein the at least one DNA barcode has greater than or equal to about 80 bases to less than or equal to about 150 bases.
3 more elements
A method of tracking and/or quantifying particulate migration, comprising:
- releasing a first plurality of particles from at least a first release location, each particle in the first plurality of particles comprising:
- a carrier comprising a non-toxic material, and
- at least one DNA barcode coupled to the carrier, wherein the DNA barcode has greater than or equal to about 80 bases to less than or equal to about 150 bases;
- collecting particles in the first plurality of particles at one or more collection locations;
- and
- analyzing the collected particles in the first plurality of particles to verify an identity thereof.
3 more elements
A method, comprising:
- providing a first carrier, wherein the first carrier is comprised of a first non-toxic material;
- coupling at least one DNA barcode to the first carrier to form a first particle;
- providing a second carrier, wherein the second carrier is comprised of a second non-toxic material;
- and
- coupling at least one DNA barcode to the second carrier to form a second particle,
- wherein the DNA barcode coupled to the first carrier is different than the DNA barcode coupled to the second carrier,
- wherein the first carrier and/or the second carrier includes an additional material coupled thereto, the additional material being selected from a group consisting of:
- a fluorophore, a protein, an immunoassay trigger, an isotope marker, a chemical signature, a sunscreen composition, and combinations thereof,
- wherein the at least one DNA barcode coupled to the first carrier and/or the second carrier has greater than or equal to about 80 bases to less than or equal to about 150 bases.
6 more elements
Dependencies are inferred from the claim text.