Methods of making hollow microneedle arrays and articles and uses therefrom

A method of manufacturing a hollow microneedle array comprising:

• (a) providing a first mold half comprising a stacked laminate mold, the stacked laminate mold comprising a plurality of plates and a plurality of cavities, wherein each of the plates comprises:
• (i) opposed first and second major surfaces;
• and
• (ii) a first mold surface connecting said first and second major surfaces;
• and wherein the plurality of cavities is open at least to the first mold surface and includes a cavity surface wherein the cavity surface intersects each respective plate's first major surface and each respective plate's first mold surface;
• (b) providing a second mold half comprising a second mold surface, wherein the second mold surface comprises a plurality of projections;
• (c) contacting at least the first mold surface or the second mold surface with polymeric material;
• and
• (d) inserting the plurality of projections into the plurality of cavities.