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US 9,287,099 B2Granted
Ionization method, mass spectrometry method, extraction method, and purification method
AssigneeCanon Kabushiki Kaisha
InventorsYoichi Otsuka, Ryuichi Arakawa
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Abstract
To achieve soft ionization more easily when a slight amount of substance is ionized under an atmosphere pressure. An ionization method for a substance contained in a liquid, including: supplying the liquid to a substrate from a probe and forming a liquid bridge made of the liquid containing the substance dissolved therein, between the probe and the substrate; oscillating the probe; and generating an electric field between an electrically conductive portion of the probe in contact with the liquid and an ion extraction electrode.
Claims15
An ionization method for a substance comprising steps of:
- (i) supplying a liquid onto a substrate from a probe such that a liquid comprising the substance bridge is formed with the liquid between the probe and the substrate, the probe having an end in-line with a longitudinal axis of the probe;
- (ii) oscillating the end of the probe in a direction that intersects with the longitudinal axis of the probe;
- and
- (iii) generating an electric field between an electrically conductive portion of the probe in contact with the liquid and an ion extraction electrode, to thereby ionize the substance contained in the liquid between the end of the probe and the ion extraction electrode.
1 more element
Dependencies are inferred from the claim text.