Systems and methods for assaying an eluate for technetium and molybdenum content
AssigneeMallinckrodt Inc.
InventorsKevin B. Graves, Bryan S. Petrofsky, Sumit Verma
Life of this patent
Estimating the term…
Abstract
A system for assaying an eluate for Technetium-99m and Molybdenum-99 content includes an inner ionization chamber including a well configured to receive the eluate, an outer ionization chamber concentric with the inner ionization chamber, and attenuating material positioned between the inner and outer ionization chambers. A computing device is configured to determine a Technetium-99m content of the eluate based on a first current measured in the inner ionization chamber, and determine a Molybdenum-99 content of the eluate based on at least a second current measured in the outer ionization chamber.
Claims20
An assaying system, comprising:
- a housing;
- a well within said housing;
- a first ionization chamber within said housing and comprising a first gas;
- a second ionization chamber within said housing and comprising a second gas;
- an attenuating material positioned between said first and second ionization chambers, wherein said first ionization chamber, said attenuating material, and said second ionization chamber are positioned relative to one another such that when an eluate is positioned within said well and emits first and second radiation:
- 1) the first radiation reaches said first ionization chamber but is blocked from reaching said second ionization chamber by said attenuating material;
- and 2) the second radiation passes through said attenuating material and reaches said second ionization chamber;
- and
- a computing device configured to:
- 1) determine a first radioisotope content based on a first current associated with said first ionization chamber;
- and 2) determine a second radioisotope content based at least on a second current associated with said second ionization chamber.
A method of assaying an eluate for first and second radioisotopes, comprising:
- measuring a first current in a first ionization chamber that is generated using first radiation emitted by an eluate and a first gas within said first ionization chamber;
- blocking said first radiation from reaching a second ionization chamber, wherein said blocking comprises using an attenuating material disposed between said first ionization chamber and a second ionization chamber;
- allowing second radiation from said eluate to reach said second ionization chamber by passing through said attenuating material;
- measuring a second current in said second ionization chamber that is generated using said second radiation emitted by said eluate and a second gas within said second ionization chamber;
- determining a first radioisotope content in said eluate using said first current;
- and
- determining a second radioisotope content in said eluate using said second current.
Dependencies are inferred from the claim text.